Conditions Contributing to Streptococcal Virulence
نویسندگان
چکیده
منابع مشابه
Virulence Traits Contributing to Pathogenicity of Candida Species
The fungus belonging to genus Candida is the only opportunistic mycotic pathogen causing a wide spectrum of clinical manifestations ranging from mucocutaneous overgrowth to life threatening disseminated infections [1]. This opportunistic fungal pathogen is ubiquitous in nature and can exist as saprophyte and commensal. However, under certain conditions Candida may transit from a commensal to a ...
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Institute of Dental Research Westmead Millennium Institutes Westmead Centre for Oral Health PO Box 533 Wentworthville NSW 2145 Tel (02) 98458772 Fax (02) 98457599 E-mail: [email protected] Infective endocarditis (IE) is a life threatening, endovascular infection occurring when bacteria enter the blood stream and adhere to heart valves. Mortality rates remain in the range of 1127% ....
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BACKGROUND Streptococcus pyogenes (group A streptococcus; GAS) is an etiological agent for pharyngitis, pyoderma, and invasive infections in humans. Pharyngitis and pyoderma may lead to serious immune sequelae such as rheumatic heart disease and post-streptococcal glomerulonephritis (PSGN). Streptococcal Inhibitor of Complement (SIC) and its orthologue, distantly related to SIC (DRS), are virul...
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Previous work has indicated a crucial role for the extracellular cysteine proteinase of Streptococcus pyogenes in the pathogenicity and virulence of this important human pathogen. Here we find that the purified streptococcal cysteine proteinase releases biologically active kinins from their purified precursor protein, H-kininogen, in vitro, and from kininogens present in the human plasma, ex vi...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1947
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.53.1.67-81.1947